The Worst Celebrity Foot-in-Mouth Moments

First, Jennifer Aniston was under fire for saying that it's OK for women to get pregnant with a "turkey baster." Now, she's said a word that even little kids know not to use.

On Thursday's live episode of "Live with Regis and Kelly," Aniston used the word "retard" to make fun of herself.

While discussing a photo shoot in which Aniston dressed up like Barbra Streisand, Aniston said, "Yes, I play dress up. I do it for a living, like a retard."

SODAHEAD SLIDESHOW: See the worst celebrity foot-in-mouth moments.

Advocacy groups hopped on the incident right away. The Special Olympics released a statement saying, "[We are] always disappointed when the R-word is used, especially by someone who is influential to society... the R-word, even in an off-the-cuff self-deprecating manner, dehumanizes people with intellectual disabilities and perpetuates painful stereotypes."

But Aniston is not alone in the open mouth, insert foot department. Dr. Laura was forced to quit her radio show after using the controversial N-word 11 times on the air last week. Mel Gibson has been caught on tape calling his ex-girlfriend every racist, sexist slur imaginable. And who can forget Michael Richards' rant, or Sinead O'Connor's grave insult to the Pope?